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A Retrospective Study of the Management of Vulvodynia

PURPOSE: Vulvodynia is characterized by chronic vulvar pain caused by sexual intercourse and often results in female sexual dysfunction. Because the causes of vulvodynia are not clear, many patients do not receive optimal treatment. Recently, gabapentin and botulinum toxin A have both been shown to...

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Autores principales: Jeon, Yongseok, Kim, Youngjun, Shim, Bosun, Yoon, Hana, Park, Youngyo, Shim, Bongsuk, Jeong, Woosik, Lee, Donghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Urological Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556554/
https://www.ncbi.nlm.nih.gov/pubmed/23362448
http://dx.doi.org/10.4111/kju.2013.54.1.48
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author Jeon, Yongseok
Kim, Youngjun
Shim, Bosun
Yoon, Hana
Park, Youngyo
Shim, Bongsuk
Jeong, Woosik
Lee, Donghyun
author_facet Jeon, Yongseok
Kim, Youngjun
Shim, Bosun
Yoon, Hana
Park, Youngyo
Shim, Bongsuk
Jeong, Woosik
Lee, Donghyun
author_sort Jeon, Yongseok
collection PubMed
description PURPOSE: Vulvodynia is characterized by chronic vulvar pain caused by sexual intercourse and often results in female sexual dysfunction. Because the causes of vulvodynia are not clear, many patients do not receive optimal treatment. Recently, gabapentin and botulinum toxin A have both been shown to be effective treatments for vulvodynia. In this study, we retrospectively analyzed the clinical outcomes of botulinum toxin A and gabapentin treatment for chronic pain in women with this condition. MATERIALS AND METHODS: Seventy-three women with vulvar pain were administered either gabapentin (n=62) or botulinum toxin A (n=11) injections. Effectiveness was measured by use of a visual analogue scale (VAS). We analyzed the treatment method, treatment duration, success of treatment, and side effects or adverse reactions. RESULTS: Pain levels in both groups significantly decreased after treatment. In the gabapentin group, the VAS score decreased from 8.6 before treatment to 3.2 after treatment (p<0.001). The VAS score in the botulinum toxin A group was reduced from 8.1 to 2.5 (p<0.001). Side effects for both therapies were few and subsided with treatment with general antibiotics and nonsteroidal antiinflammatory drugs. CONCLUSIONS: Gabapentin and botulinum toxin A are safe and effective treatments for vulvodynia. This condition can cause sexual dysfunction and affect quality of life. However, with proper management, satisfactory outcomes for women with vulvodynia can be achieved.
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spelling pubmed-35565542013-01-29 A Retrospective Study of the Management of Vulvodynia Jeon, Yongseok Kim, Youngjun Shim, Bosun Yoon, Hana Park, Youngyo Shim, Bongsuk Jeong, Woosik Lee, Donghyun Korean J Urol Original Article PURPOSE: Vulvodynia is characterized by chronic vulvar pain caused by sexual intercourse and often results in female sexual dysfunction. Because the causes of vulvodynia are not clear, many patients do not receive optimal treatment. Recently, gabapentin and botulinum toxin A have both been shown to be effective treatments for vulvodynia. In this study, we retrospectively analyzed the clinical outcomes of botulinum toxin A and gabapentin treatment for chronic pain in women with this condition. MATERIALS AND METHODS: Seventy-three women with vulvar pain were administered either gabapentin (n=62) or botulinum toxin A (n=11) injections. Effectiveness was measured by use of a visual analogue scale (VAS). We analyzed the treatment method, treatment duration, success of treatment, and side effects or adverse reactions. RESULTS: Pain levels in both groups significantly decreased after treatment. In the gabapentin group, the VAS score decreased from 8.6 before treatment to 3.2 after treatment (p<0.001). The VAS score in the botulinum toxin A group was reduced from 8.1 to 2.5 (p<0.001). Side effects for both therapies were few and subsided with treatment with general antibiotics and nonsteroidal antiinflammatory drugs. CONCLUSIONS: Gabapentin and botulinum toxin A are safe and effective treatments for vulvodynia. This condition can cause sexual dysfunction and affect quality of life. However, with proper management, satisfactory outcomes for women with vulvodynia can be achieved. The Korean Urological Association 2013-01 2013-01-18 /pmc/articles/PMC3556554/ /pubmed/23362448 http://dx.doi.org/10.4111/kju.2013.54.1.48 Text en © The Korean Urological Association, 2013 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jeon, Yongseok
Kim, Youngjun
Shim, Bosun
Yoon, Hana
Park, Youngyo
Shim, Bongsuk
Jeong, Woosik
Lee, Donghyun
A Retrospective Study of the Management of Vulvodynia
title A Retrospective Study of the Management of Vulvodynia
title_full A Retrospective Study of the Management of Vulvodynia
title_fullStr A Retrospective Study of the Management of Vulvodynia
title_full_unstemmed A Retrospective Study of the Management of Vulvodynia
title_short A Retrospective Study of the Management of Vulvodynia
title_sort retrospective study of the management of vulvodynia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556554/
https://www.ncbi.nlm.nih.gov/pubmed/23362448
http://dx.doi.org/10.4111/kju.2013.54.1.48
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