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Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study

Background: Childhood asthma morbidity and mortality in New Orleans, Louisiana, is among the highest in the nation. In August 2005, Hurricane Katrina created an environmental disaster that led to high levels of mold and other allergens and disrupted health care for children with asthma. Objectives:...

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Autores principales: Mitchell, Herman, Cohn, Richard D., Wildfire, Jeremy, Thornton, Eleanor, Kennedy, Suzanne, El-Dahr, Jane M., Chulada, Patricia C., Mvula, Mosanda M., Grimsley, L. Faye, Lichtveld, Maureen Y., White, LuAnn E., Sterling, Yvonne M., Stephens, Kevin U., Martin, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556603/
https://www.ncbi.nlm.nih.gov/pubmed/22894795
http://dx.doi.org/10.1289/ehp.1104242
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author Mitchell, Herman
Cohn, Richard D.
Wildfire, Jeremy
Thornton, Eleanor
Kennedy, Suzanne
El-Dahr, Jane M.
Chulada, Patricia C.
Mvula, Mosanda M.
Grimsley, L. Faye
Lichtveld, Maureen Y.
White, LuAnn E.
Sterling, Yvonne M.
Stephens, Kevin U.
Martin, William J.
author_facet Mitchell, Herman
Cohn, Richard D.
Wildfire, Jeremy
Thornton, Eleanor
Kennedy, Suzanne
El-Dahr, Jane M.
Chulada, Patricia C.
Mvula, Mosanda M.
Grimsley, L. Faye
Lichtveld, Maureen Y.
White, LuAnn E.
Sterling, Yvonne M.
Stephens, Kevin U.
Martin, William J.
author_sort Mitchell, Herman
collection PubMed
description Background: Childhood asthma morbidity and mortality in New Orleans, Louisiana, is among the highest in the nation. In August 2005, Hurricane Katrina created an environmental disaster that led to high levels of mold and other allergens and disrupted health care for children with asthma. Objectives: We implemented a unique hybrid asthma counselor and environmental intervention based on successful National Institutes of Health asthma interventions from the National Cooperative Inner City Asthma (NCICAS) and Inner-City Asthma (ICAS) Studies with the goal of reducing asthma symptoms in New Orleans children after Hurricane Katrina. Methods: Children (4–12 years old) with moderate-to-severe asthma (n = 182) received asthma counseling and environmental intervention for approximately 1 year. HEAL was evaluated employing several analytical approaches including a pre–post evaluation of symptom changes over the entire year, an analysis of symptoms according to the timing of asthma counselor contact, and a comparison to previous evidence-based interventions. Results: Asthma symptoms during the previous 2 weeks decreased from 6.5 days at enrollment to 3.6 days at the 12-month symptom assessment (a 45% reduction, p < 0.001), consistent with changes observed after NCICAS and ICAS interventions (35% and 62% reductions in symptom days, respectively). Children whose families had contact with a HEAL asthma counselor by 6 months showed a 4.09-day decrease [95% confidence interval (CI): 3.25 to 4.94-day decrease] in symptom days, compared with a 1.79-day decrease (95% CI: 0.90, 2.67) among those who had not yet seen an asthma counselor (p < 0.001). Conclusions: The novel combination of evidence-based asthma interventions was associated with improved asthma symptoms among children in post-Katrina New Orleans. Post-intervention changes in symptoms were consistent with previous randomized trials of NCICAS and ICAS interventions.
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spelling pubmed-35566032013-01-30 Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study Mitchell, Herman Cohn, Richard D. Wildfire, Jeremy Thornton, Eleanor Kennedy, Suzanne El-Dahr, Jane M. Chulada, Patricia C. Mvula, Mosanda M. Grimsley, L. Faye Lichtveld, Maureen Y. White, LuAnn E. Sterling, Yvonne M. Stephens, Kevin U. Martin, William J. Environ Health Perspect Research Background: Childhood asthma morbidity and mortality in New Orleans, Louisiana, is among the highest in the nation. In August 2005, Hurricane Katrina created an environmental disaster that led to high levels of mold and other allergens and disrupted health care for children with asthma. Objectives: We implemented a unique hybrid asthma counselor and environmental intervention based on successful National Institutes of Health asthma interventions from the National Cooperative Inner City Asthma (NCICAS) and Inner-City Asthma (ICAS) Studies with the goal of reducing asthma symptoms in New Orleans children after Hurricane Katrina. Methods: Children (4–12 years old) with moderate-to-severe asthma (n = 182) received asthma counseling and environmental intervention for approximately 1 year. HEAL was evaluated employing several analytical approaches including a pre–post evaluation of symptom changes over the entire year, an analysis of symptoms according to the timing of asthma counselor contact, and a comparison to previous evidence-based interventions. Results: Asthma symptoms during the previous 2 weeks decreased from 6.5 days at enrollment to 3.6 days at the 12-month symptom assessment (a 45% reduction, p < 0.001), consistent with changes observed after NCICAS and ICAS interventions (35% and 62% reductions in symptom days, respectively). Children whose families had contact with a HEAL asthma counselor by 6 months showed a 4.09-day decrease [95% confidence interval (CI): 3.25 to 4.94-day decrease] in symptom days, compared with a 1.79-day decrease (95% CI: 0.90, 2.67) among those who had not yet seen an asthma counselor (p < 0.001). Conclusions: The novel combination of evidence-based asthma interventions was associated with improved asthma symptoms among children in post-Katrina New Orleans. Post-intervention changes in symptoms were consistent with previous randomized trials of NCICAS and ICAS interventions. National Institute of Environmental Health Sciences 2012-08-15 2012-11 /pmc/articles/PMC3556603/ /pubmed/22894795 http://dx.doi.org/10.1289/ehp.1104242 Text en http://creativecommons.org/publicdomain/mark/1.0/ Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, ?Reproduced with permission from Environmental Health Perspectives?); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.
spellingShingle Research
Mitchell, Herman
Cohn, Richard D.
Wildfire, Jeremy
Thornton, Eleanor
Kennedy, Suzanne
El-Dahr, Jane M.
Chulada, Patricia C.
Mvula, Mosanda M.
Grimsley, L. Faye
Lichtveld, Maureen Y.
White, LuAnn E.
Sterling, Yvonne M.
Stephens, Kevin U.
Martin, William J.
Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study
title Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study
title_full Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study
title_fullStr Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study
title_full_unstemmed Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study
title_short Implementation of Evidence-based Asthma Interventions in Post-Katrina New Orleans: The Head-off Environmental Asthma in Louisiana (HEAL) Study
title_sort implementation of evidence-based asthma interventions in post-katrina new orleans: the head-off environmental asthma in louisiana (heal) study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556603/
https://www.ncbi.nlm.nih.gov/pubmed/22894795
http://dx.doi.org/10.1289/ehp.1104242
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