De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia

To evaluate evidence for de novo etiologies in schizophrenia, we sequenced at high coverage the exomes of families recruited from two populations with distinct demographic structure and history. We sequenced a total of 795 exomes from 231 parent-proband trios enriched for sporadic schizophrenia case...

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Detalles Bibliográficos
Autores principales: Xu, Bin, Ionita-Laza, Iuliana, Roos, J. Louw, Boone, Braden, Woodrick, Scarlet, Sun, Yan, Levy, Shawn, Gogos, Joseph A., Karayiorgou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556813/
https://www.ncbi.nlm.nih.gov/pubmed/23042115
http://dx.doi.org/10.1038/ng.2446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556813/
https://www.ncbi.nlm.nih.gov/pubmed/23042115
http://dx.doi.org/10.1038/ng.2446

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