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Computational and Bioinformatics Frameworks for Next-Generation Whole Exome and Genome Sequencing
It has become increasingly apparent that one of the major hurdles in the genomic age will be the bioinformatics challenges of next-generation sequencing. We provide an overview of a general framework of bioinformatics analysis. For each of the three stages of (1) alignment, (2) variant calling, and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556895/ https://www.ncbi.nlm.nih.gov/pubmed/23365548 http://dx.doi.org/10.1155/2013/730210 |