The combined use of paclitaxel-loaded nanoparticles with a low-molecular-weight copolymer inhibitor of P-glycoprotein to overcome drug resistance

Two types of nanoparticles were prepared using the diblock copolymer methoxy poly(ethylene glycol)-block-poly(caprolactone) (MePEG-b-PCL), with either a short PCL block length, which forms micelles, or with a longer PCL block length, which forms kinetically “frozen core” structures termed nanosphere...

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Detalles Bibliográficos
Autores principales: Wan, Chung Ping Leon, Letchford, Kevin, Jackson, John K, Burt, Helen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556923/
https://www.ncbi.nlm.nih.gov/pubmed/23378760
http://dx.doi.org/10.2147/IJN.S38737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556923/
https://www.ncbi.nlm.nih.gov/pubmed/23378760
http://dx.doi.org/10.2147/IJN.S38737

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