Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction

The synthesis of dipyrazolo[1,5-a:4',3'-c]pyridines is described. Easily obtainable 5-alkynylpyrazole-4-carbaldehydes, p-toluenesulfonyl hydrazide, and an aldehyde or ketone containing an α-hydrogen atom were reacted in a silver triflate catalyzed multicomponent reaction affording new tric...

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Autores principales: Holzer, Wolfgang, Vilkauskaitė, Gytė, Arbačiauskienė, Eglė, Šačkus, Algirdas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557119/
https://www.ncbi.nlm.nih.gov/pubmed/23365633
http://dx.doi.org/10.3762/bjoc.8.251
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author Holzer, Wolfgang
Vilkauskaitė, Gytė
Arbačiauskienė, Eglė
Šačkus, Algirdas
author_facet Holzer, Wolfgang
Vilkauskaitė, Gytė
Arbačiauskienė, Eglė
Šačkus, Algirdas
author_sort Holzer, Wolfgang
collection PubMed
description The synthesis of dipyrazolo[1,5-a:4',3'-c]pyridines is described. Easily obtainable 5-alkynylpyrazole-4-carbaldehydes, p-toluenesulfonyl hydrazide, and an aldehyde or ketone containing an α-hydrogen atom were reacted in a silver triflate catalyzed multicomponent reaction affording new tricyclic compounds with a dipyrazolo[1,5-a:4',3'-c]pyridine core. Detailed NMR spectroscopic investigations ((1)H, (13)C and (15)N) were undertaken with all obtained compounds.
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spelling pubmed-35571192013-01-30 Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction Holzer, Wolfgang Vilkauskaitė, Gytė Arbačiauskienė, Eglė Šačkus, Algirdas Beilstein J Org Chem Full Research Paper The synthesis of dipyrazolo[1,5-a:4',3'-c]pyridines is described. Easily obtainable 5-alkynylpyrazole-4-carbaldehydes, p-toluenesulfonyl hydrazide, and an aldehyde or ketone containing an α-hydrogen atom were reacted in a silver triflate catalyzed multicomponent reaction affording new tricyclic compounds with a dipyrazolo[1,5-a:4',3'-c]pyridine core. Detailed NMR spectroscopic investigations ((1)H, (13)C and (15)N) were undertaken with all obtained compounds. Beilstein-Institut 2012-12-27 /pmc/articles/PMC3557119/ /pubmed/23365633 http://dx.doi.org/10.3762/bjoc.8.251 Text en Copyright © 2012, Holzer et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Holzer, Wolfgang
Vilkauskaitė, Gytė
Arbačiauskienė, Eglė
Šačkus, Algirdas
Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
title Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
title_full Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
title_fullStr Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
title_full_unstemmed Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
title_short Dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
title_sort dipyrazolo[1,5-a:4',3'-c]pyridines – a new heterocyclic system accessed via multicomponent reaction
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557119/
https://www.ncbi.nlm.nih.gov/pubmed/23365633
http://dx.doi.org/10.3762/bjoc.8.251
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