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Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer
BACKGROUND: G-protein-coupled estrogen receptor (GPER/GPR30) was reported to bind 17β-estradiol (E(2)), tamoxifen, and ICI 182,780 (fulvestrant) and promotes activation of epidermal growth factor receptor (EGFR)-mediated signaling in breast, endometrial and thyroid cancer cells. Although lung adenoc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557142/ https://www.ncbi.nlm.nih.gov/pubmed/23273253 http://dx.doi.org/10.1186/1471-2407-12-624 |