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Applying data mining techniques to improve diagnosis in neonatal jaundice

BACKGROUND: Hyperbilirubinemia is emerging as an increasingly common problem in newborns due to a decreasing hospital length of stay after birth. Jaundice is the most common disease of the newborn and although being benign in most cases it can lead to severe neurological consequences if poorly evalu...

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Autores principales: Ferreira, Duarte, Oliveira, Abílio, Freitas, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557145/
https://www.ncbi.nlm.nih.gov/pubmed/23216895
http://dx.doi.org/10.1186/1472-6947-12-143
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author Ferreira, Duarte
Oliveira, Abílio
Freitas, Alberto
author_facet Ferreira, Duarte
Oliveira, Abílio
Freitas, Alberto
author_sort Ferreira, Duarte
collection PubMed
description BACKGROUND: Hyperbilirubinemia is emerging as an increasingly common problem in newborns due to a decreasing hospital length of stay after birth. Jaundice is the most common disease of the newborn and although being benign in most cases it can lead to severe neurological consequences if poorly evaluated. In different areas of medicine, data mining has contributed to improve the results obtained with other methodologies. Hence, the aim of this study was to improve the diagnosis of neonatal jaundice with the application of data mining techniques. METHODS: This study followed the different phases of the Cross Industry Standard Process for Data Mining model as its methodology. This observational study was performed at the Obstetrics Department of a central hospital (Centro Hospitalar Tâmega e Sousa – EPE), from February to March of 2011. A total of 227 healthy newborn infants with 35 or more weeks of gestation were enrolled in the study. Over 70 variables were collected and analyzed. Also, transcutaneous bilirubin levels were measured from birth to hospital discharge with maximum time intervals of 8 hours between measurements, using a noninvasive bilirubinometer. Different attribute subsets were used to train and test classification models using algorithms included in Weka data mining software, such as decision trees (J48) and neural networks (multilayer perceptron). The accuracy results were compared with the traditional methods for prediction of hyperbilirubinemia. RESULTS: The application of different classification algorithms to the collected data allowed predicting subsequent hyperbilirubinemia with high accuracy. In particular, at 24 hours of life of newborns, the accuracy for the prediction of hyperbilirubinemia was 89%. The best results were obtained using the following algorithms: naive Bayes, multilayer perceptron and simple logistic. CONCLUSIONS: The findings of our study sustain that, new approaches, such as data mining, may support medical decision, contributing to improve diagnosis in neonatal jaundice.
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spelling pubmed-35571452013-01-31 Applying data mining techniques to improve diagnosis in neonatal jaundice Ferreira, Duarte Oliveira, Abílio Freitas, Alberto BMC Med Inform Decis Mak Research Article BACKGROUND: Hyperbilirubinemia is emerging as an increasingly common problem in newborns due to a decreasing hospital length of stay after birth. Jaundice is the most common disease of the newborn and although being benign in most cases it can lead to severe neurological consequences if poorly evaluated. In different areas of medicine, data mining has contributed to improve the results obtained with other methodologies. Hence, the aim of this study was to improve the diagnosis of neonatal jaundice with the application of data mining techniques. METHODS: This study followed the different phases of the Cross Industry Standard Process for Data Mining model as its methodology. This observational study was performed at the Obstetrics Department of a central hospital (Centro Hospitalar Tâmega e Sousa – EPE), from February to March of 2011. A total of 227 healthy newborn infants with 35 or more weeks of gestation were enrolled in the study. Over 70 variables were collected and analyzed. Also, transcutaneous bilirubin levels were measured from birth to hospital discharge with maximum time intervals of 8 hours between measurements, using a noninvasive bilirubinometer. Different attribute subsets were used to train and test classification models using algorithms included in Weka data mining software, such as decision trees (J48) and neural networks (multilayer perceptron). The accuracy results were compared with the traditional methods for prediction of hyperbilirubinemia. RESULTS: The application of different classification algorithms to the collected data allowed predicting subsequent hyperbilirubinemia with high accuracy. In particular, at 24 hours of life of newborns, the accuracy for the prediction of hyperbilirubinemia was 89%. The best results were obtained using the following algorithms: naive Bayes, multilayer perceptron and simple logistic. CONCLUSIONS: The findings of our study sustain that, new approaches, such as data mining, may support medical decision, contributing to improve diagnosis in neonatal jaundice. BioMed Central 2012-12-07 /pmc/articles/PMC3557145/ /pubmed/23216895 http://dx.doi.org/10.1186/1472-6947-12-143 Text en Copyright ©2012 Ferreira et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ferreira, Duarte
Oliveira, Abílio
Freitas, Alberto
Applying data mining techniques to improve diagnosis in neonatal jaundice
title Applying data mining techniques to improve diagnosis in neonatal jaundice
title_full Applying data mining techniques to improve diagnosis in neonatal jaundice
title_fullStr Applying data mining techniques to improve diagnosis in neonatal jaundice
title_full_unstemmed Applying data mining techniques to improve diagnosis in neonatal jaundice
title_short Applying data mining techniques to improve diagnosis in neonatal jaundice
title_sort applying data mining techniques to improve diagnosis in neonatal jaundice
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557145/
https://www.ncbi.nlm.nih.gov/pubmed/23216895
http://dx.doi.org/10.1186/1472-6947-12-143
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