The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice

BACKGROUND: Sepsis has been identified as the most common cause of acute kidney injury (AKI) in intensive care units. Lipopolysaccharide (LPS) induces the production of several proinflammatory cytokines including tumor necrosis factor (TNF)-alpha, a major pathogenetic factor in septic AKI. c-Fos/act...

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Detalles Bibliográficos
Autores principales: Miyazaki, Hiroyuki, Morishita, Jun, Ueki, Masaaki, Nishina, Kahoru, Shiozawa, Shunichi, Maekawa, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557146/
https://www.ncbi.nlm.nih.gov/pubmed/23173923
http://dx.doi.org/10.1186/1471-2369-13-153

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