Cargando…

Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages

BACKGROUND: The goal of malaria elimination necessitates an improved understanding of any fine-scale geographic variations in transmission risk so that complementary vector control tools can be integrated into current vector control programmes as supplementary measures that are spatially targeted to...

Descripción completa

Detalles Bibliográficos
Autores principales: Russell, Tanya L, Lwetoijera, Dickson W, Knols, Bart GJ, Takken, Willem, Killeen, Gerry F, Kelly-Hope, Louise A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557203/
https://www.ncbi.nlm.nih.gov/pubmed/23331947
http://dx.doi.org/10.1186/1475-2875-12-24
_version_ 1782257283600744448
author Russell, Tanya L
Lwetoijera, Dickson W
Knols, Bart GJ
Takken, Willem
Killeen, Gerry F
Kelly-Hope, Louise A
author_facet Russell, Tanya L
Lwetoijera, Dickson W
Knols, Bart GJ
Takken, Willem
Killeen, Gerry F
Kelly-Hope, Louise A
author_sort Russell, Tanya L
collection PubMed
description BACKGROUND: The goal of malaria elimination necessitates an improved understanding of any fine-scale geographic variations in transmission risk so that complementary vector control tools can be integrated into current vector control programmes as supplementary measures that are spatially targeted to maximize impact upon residual transmission. This study examines the distribution of host-seeking malaria vectors at households within two villages in rural Tanzania. METHODS: Host-seeking mosquitoes were sampled from 72 randomly selected households in two villages on a monthly basis throughout 2008 using CDC light-traps placed beside occupied nets. Spatial autocorrelation in the dataset was examined using the Moran’s I statistic and the location of any clusters was identified using the Getis-Ord Gi* statistic. Statistical associations between the household characteristics and clusters of mosquitoes were assessed using a generalized linear model for each species. RESULTS: For both Anopheles gambiae sensu lato and Anopheles funestus, the density of host-seeking females was spatially autocorrelated, or clustered. For both species, houses with low densities were clustered in the semi-urban village centre while houses with high densities were clustered in the periphery of the villages. Clusters of houses with low or high densities of An. gambiae s.l. were influenced by the number of residents in nearby houses. The occurrence of high-density clusters of An. gambiae s.l. was associated with lower elevations while An. funestus was also associated with higher elevations. Distance from the village centre was also positively correlated with the number of household occupants and having houses constructed with open eaves. CONCLUSION: The results of the current study highlight that complementary vector control tools could be most effectively targeted to the periphery of villages where the households potentially have a higher hazard (mosquito densities) and vulnerability (open eaves and larger households) to malaria infection.
format Online
Article
Text
id pubmed-3557203
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-35572032013-01-31 Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages Russell, Tanya L Lwetoijera, Dickson W Knols, Bart GJ Takken, Willem Killeen, Gerry F Kelly-Hope, Louise A Malar J Research BACKGROUND: The goal of malaria elimination necessitates an improved understanding of any fine-scale geographic variations in transmission risk so that complementary vector control tools can be integrated into current vector control programmes as supplementary measures that are spatially targeted to maximize impact upon residual transmission. This study examines the distribution of host-seeking malaria vectors at households within two villages in rural Tanzania. METHODS: Host-seeking mosquitoes were sampled from 72 randomly selected households in two villages on a monthly basis throughout 2008 using CDC light-traps placed beside occupied nets. Spatial autocorrelation in the dataset was examined using the Moran’s I statistic and the location of any clusters was identified using the Getis-Ord Gi* statistic. Statistical associations between the household characteristics and clusters of mosquitoes were assessed using a generalized linear model for each species. RESULTS: For both Anopheles gambiae sensu lato and Anopheles funestus, the density of host-seeking females was spatially autocorrelated, or clustered. For both species, houses with low densities were clustered in the semi-urban village centre while houses with high densities were clustered in the periphery of the villages. Clusters of houses with low or high densities of An. gambiae s.l. were influenced by the number of residents in nearby houses. The occurrence of high-density clusters of An. gambiae s.l. was associated with lower elevations while An. funestus was also associated with higher elevations. Distance from the village centre was also positively correlated with the number of household occupants and having houses constructed with open eaves. CONCLUSION: The results of the current study highlight that complementary vector control tools could be most effectively targeted to the periphery of villages where the households potentially have a higher hazard (mosquito densities) and vulnerability (open eaves and larger households) to malaria infection. BioMed Central 2013-01-18 /pmc/articles/PMC3557203/ /pubmed/23331947 http://dx.doi.org/10.1186/1475-2875-12-24 Text en Copyright ©2013 Russell et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Russell, Tanya L
Lwetoijera, Dickson W
Knols, Bart GJ
Takken, Willem
Killeen, Gerry F
Kelly-Hope, Louise A
Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages
title Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages
title_full Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages
title_fullStr Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages
title_full_unstemmed Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages
title_short Geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two Tanzanian villages
title_sort geographic coincidence of increased malaria transmission hazard and vulnerability occurring at the periphery of two tanzanian villages
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557203/
https://www.ncbi.nlm.nih.gov/pubmed/23331947
http://dx.doi.org/10.1186/1475-2875-12-24
work_keys_str_mv AT russelltanyal geographiccoincidenceofincreasedmalariatransmissionhazardandvulnerabilityoccurringattheperipheryoftwotanzanianvillages
AT lwetoijeradicksonw geographiccoincidenceofincreasedmalariatransmissionhazardandvulnerabilityoccurringattheperipheryoftwotanzanianvillages
AT knolsbartgj geographiccoincidenceofincreasedmalariatransmissionhazardandvulnerabilityoccurringattheperipheryoftwotanzanianvillages
AT takkenwillem geographiccoincidenceofincreasedmalariatransmissionhazardandvulnerabilityoccurringattheperipheryoftwotanzanianvillages
AT killeengerryf geographiccoincidenceofincreasedmalariatransmissionhazardandvulnerabilityoccurringattheperipheryoftwotanzanianvillages
AT kellyhopelouisea geographiccoincidenceofincreasedmalariatransmissionhazardandvulnerabilityoccurringattheperipheryoftwotanzanianvillages