Deficiencies of the Lipid-Signaling Enzymes Phospholipase D1 and D2 Alter Cytoskeletal Organization, Macrophage Phagocytosis, and Cytokine-Stimulated Neutrophil Recruitment

Cell migration and phagocytosis ensue from extracellular-initiated signaling cascades that orchestrate dynamic reorganization of the actin cytoskeleton. The reorganization is mediated by effector proteins recruited to the site of activity by locally-generated lipid second messengers. Phosphatidic ac...

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Detalles Bibliográficos
Autores principales: Ali, Wahida H., Chen, Qin, Delgiorno, Kathleen E., Su, Wenjuan, Hall, Jason C., Hongu, Tsunaki, Tian, Huasong, Kanaho, Yasunori, Di Paolo, Gilbert, Crawford, Howard C., Frohman, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557251/
https://www.ncbi.nlm.nih.gov/pubmed/23383154
http://dx.doi.org/10.1371/journal.pone.0055325

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