Cargando…
Interaction between residues in the Mg(2+)-binding site regulates BK channel activation
As a unique member of the voltage-gated potassium channel family, a large conductance, voltage- and Ca(2+)-activated K(+) (BK) channel has a large cytosolic domain that serves as the Ca(2+) sensor, in addition to a membrane-spanning domain that contains the voltage-sensing (VSD) and pore-gate domain...
Autores principales: | Yang, Junqiu, Yang, Huanghe, Sun, Xiaohui, Delaloye, Kelli, Yang, Xiao, Moller, Alyssa, Shi, Jingyi, Cui, Jianmin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557308/ https://www.ncbi.nlm.nih.gov/pubmed/23359284 http://dx.doi.org/10.1085/jgp.201210794 |
Ejemplares similares
-
Activation of Slo1 BK channels by Mg(2+) coordinated between the voltage sensor and the RCK1 domains
por: Yang, Huanghe, et al.
Publicado: (2008) -
Effects of Multiple Metal Binding Sites on Calcium and Magnesium-dependent Activation of BK Channels
por: Hu, Lei, et al.
Publicado: (2006) -
BK channels: multiple sensors, one activation gate
por: Yang, Huanghe, et al.
Publicado: (2015) -
Intracellular Mg(2+) Enhances the Function of Bk-Type Ca(2+)-Activated K(+) Channels
por: Shi, Jingyi, et al.
Publicado: (2001) -
Aromatic interactions with membrane modulate human BK channel activation
por: Yazdani, Mahdieh, et al.
Publicado: (2020)