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The eag domain regulates hERG channel inactivation gating via a direct interaction

Human ether-á-go-go (eag)-related gene (hERG) potassium channel kinetics are characterized by rapid inactivation upon depolarization, along with rapid recovery from inactivation and very slow closing (deactivation) upon repolarization. These factors combine to create a resurgent hERG current, where...

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Detalles Bibliográficos
Autores principales:	Gustina, Ahleah S., Trudeau, Matthew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557309/ https://www.ncbi.nlm.nih.gov/pubmed/23319729 http://dx.doi.org/10.1085/jgp.201210870

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