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Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1
Mesalamine (5-ASA) is widely used for the treatment of ulcerative colitis, a remitting condition characterized by chronic inflammation of the colon. Knowledge about the molecular and cellular targets of 5-ASA is limited and a clear understanding of its activity in intestinal homeostasis and interfer...
Autores principales: | Khare, Vineeta, Lyakhovich, Alex, Dammann, Kyle, Lang, Michaela, Borgmann, Melanie, Tichy, Boris, Pospisilova, Sarka, Luciani, Gloria, Campregher, Christoph, Evstatiev, Rayko, Pflueger, Maren, Hundsberger, Harald, Gasche, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557386/ https://www.ncbi.nlm.nih.gov/pubmed/23146664 http://dx.doi.org/10.1016/j.bcp.2012.10.026 |
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