Brain penetration of the OAB drug trospium chloride is not increased in aged mice

PURPOSE: To analyse whether the permeability of the blood–brain barrier to the antimuscarinic drug trospium chloride is altered with ageing. This is a relevant question for elderly patients with overactive bladder syndrome who are treated with trospium chloride as the occurrence of adverse effects o...

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Detalles Bibliográficos
Autores principales: Kranz, Jasmin, Petzinger, Ernst, Geyer, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557395/
https://www.ncbi.nlm.nih.gov/pubmed/22120415
http://dx.doi.org/10.1007/s00345-011-0803-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557395/
https://www.ncbi.nlm.nih.gov/pubmed/22120415
http://dx.doi.org/10.1007/s00345-011-0803-z

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