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Brain penetration of the OAB drug trospium chloride is not increased in aged mice

PURPOSE: To analyse whether the permeability of the blood–brain barrier to the antimuscarinic drug trospium chloride is altered with ageing. This is a relevant question for elderly patients with overactive bladder syndrome who are treated with trospium chloride as the occurrence of adverse effects o...

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Detalles Bibliográficos
Autores principales:	Kranz, Jasmin, Petzinger, Ernst, Geyer, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557395/ https://www.ncbi.nlm.nih.gov/pubmed/22120415 http://dx.doi.org/10.1007/s00345-011-0803-z

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