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SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites

The Class IIa histone deacetylases (HDAC)4 and HDAC5 play a role in neuronal survival and behavioral adaptation in the CNS. Phosphorylation at 2/3 N-terminal sites promote their nuclear export. We investigated whether non-canonical signaling routes to Class IIa HDAC export exist because of their ass...

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Detalles Bibliográficos
Autores principales:	Soriano, Francesc X, Chawla, Sangeeta, Skehel, Paul, Hardingham, Giles E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557716/ https://www.ncbi.nlm.nih.gov/pubmed/23083128 http://dx.doi.org/10.1111/jnc.12058

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