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Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010
The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioido...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557896/ https://www.ncbi.nlm.nih.gov/pubmed/23171644 http://dx.doi.org/10.3201/eid1812.120638 |
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author | Lipsitz, Rebecca Garges, Susan Aurigemma, Rosemarie Baccam, Prasith Blaney, David D. Cheng, Allen C. Currie, Bart J. Dance, David Gee, Jay E. Larsen, Joseph Limmathurotsakul, Direk Morrow, Meredith G. Norton, Robert O’Mara, Elizabeth Peacock, Sharon J. Pesik, Nicki Rogers, L. Paige Schweizer, Herbert P. Steinmetz, Ivo Tan, Gladys Tan, Patrick Wiersinga, W. Joost Wuthiekanun, Vanaporn Smith, Theresa L. |
author_facet | Lipsitz, Rebecca Garges, Susan Aurigemma, Rosemarie Baccam, Prasith Blaney, David D. Cheng, Allen C. Currie, Bart J. Dance, David Gee, Jay E. Larsen, Joseph Limmathurotsakul, Direk Morrow, Meredith G. Norton, Robert O’Mara, Elizabeth Peacock, Sharon J. Pesik, Nicki Rogers, L. Paige Schweizer, Herbert P. Steinmetz, Ivo Tan, Gladys Tan, Patrick Wiersinga, W. Joost Wuthiekanun, Vanaporn Smith, Theresa L. |
author_sort | Lipsitz, Rebecca |
collection | PubMed |
description | The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options. |
format | Online Article Text |
id | pubmed-3557896 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-35578962013-02-04 Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 Lipsitz, Rebecca Garges, Susan Aurigemma, Rosemarie Baccam, Prasith Blaney, David D. Cheng, Allen C. Currie, Bart J. Dance, David Gee, Jay E. Larsen, Joseph Limmathurotsakul, Direk Morrow, Meredith G. Norton, Robert O’Mara, Elizabeth Peacock, Sharon J. Pesik, Nicki Rogers, L. Paige Schweizer, Herbert P. Steinmetz, Ivo Tan, Gladys Tan, Patrick Wiersinga, W. Joost Wuthiekanun, Vanaporn Smith, Theresa L. Emerg Infect Dis Online Report The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomallei and B. mallei infections, which cause melioidosis and glanders, respectively. Drugs recommended by consensus of the participants are ceftazidime or meropenem for initial intensive therapy, and trimethoprim/sulfamethoxazole or amoxicillin/clavulanic acid for eradication therapy. For postexposure prophylaxis, recommended drugs are trimethoprim/sulfamethoxazole or co-amoxiclav. To improve the timely diagnosis of melioidosis and glanders, further development and wide distribution of rapid diagnostic assays were also recommended. Standardized animal models and B. pseudomallei strains are needed for further development of therapeutic options. Training for laboratory technicians and physicians would facilitate better diagnosis and treatment options. Centers for Disease Control and Prevention 2012-12 /pmc/articles/PMC3557896/ /pubmed/23171644 http://dx.doi.org/10.3201/eid1812.120638 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Online Report Lipsitz, Rebecca Garges, Susan Aurigemma, Rosemarie Baccam, Prasith Blaney, David D. Cheng, Allen C. Currie, Bart J. Dance, David Gee, Jay E. Larsen, Joseph Limmathurotsakul, Direk Morrow, Meredith G. Norton, Robert O’Mara, Elizabeth Peacock, Sharon J. Pesik, Nicki Rogers, L. Paige Schweizer, Herbert P. Steinmetz, Ivo Tan, Gladys Tan, Patrick Wiersinga, W. Joost Wuthiekanun, Vanaporn Smith, Theresa L. Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
title | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
title_full | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
title_fullStr | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
title_full_unstemmed | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
title_short | Workshop on Treatment of and Postexposure Prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010 |
title_sort | workshop on treatment of and postexposure prophylaxis for burkholderia pseudomallei and b. mallei infection, 2010 |
topic | Online Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557896/ https://www.ncbi.nlm.nih.gov/pubmed/23171644 http://dx.doi.org/10.3201/eid1812.120638 |
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