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Theoretical Investigations and Density Functional Theory Based Quantitative Structure–Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes

[Image: see text] Octahedral platinum(IV) complexes are promising candidates in the fight against cancer. In order to rationalize the further development of this class of compounds, detailed studies on their mechanisms of action, toxicity, and resistance must be provided and structure–activity relat...

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Detalles Bibliográficos
Autores principales:	Varbanov, Hristo P., Jakupec, Michael A., Roller, Alexander, Jensen, Frank, Galanski, Markus, Keppler, Bernhard K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2012
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557934/ https://www.ncbi.nlm.nih.gov/pubmed/23214999 http://dx.doi.org/10.1021/jm3016427

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