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Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma
Neuroblastomas are tumors of peripheral sympathetic neurons and are the most common solid tumor in children. To determine the genetic basis for neuroblastoma we performed whole-genome sequencing (6 cases), exome sequencing (16 cases), genome-wide rearrangement analyses (32 cases), and targeted analy...
Autores principales: | Sausen, Mark, Leary, Rebecca J., Jones, Siân, Wu, Jian, Reynolds, C. Patrick, Liu, Xueyuan, Blackford, Amanda, Parmigiani, Giovanni, Diaz, Luis A., Papadopoulos, Nickolas, Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E., Hogarty, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557959/ https://www.ncbi.nlm.nih.gov/pubmed/23202128 http://dx.doi.org/10.1038/ng.2493 |
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