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Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783

BACKGROUND: Phosphatase of regenerating liver-3 (PRL-3 or PTP4A3) has been implicated in controlling cancer cell proliferation, motility, metastasis, and angiogenesis. Deregulated expression of PRL-3 is highly correlated with cancer progression and predicts poor survival. Although PRL-3 was categori...

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Detalles Bibliográficos
Autores principales: Tian, Wei, Qu, Like, Meng, Lin, Liu, Caiyun, Wu, Jian, Shou, Chengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558359/
https://www.ncbi.nlm.nih.gov/pubmed/23092334
http://dx.doi.org/10.1186/1471-2091-13-22