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p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI)

BACKGROUND: Neuropathic pain is detrimental to human health; however, its pathogenesis still remains largely unknown. Overexpression of pain-associated genes and increased nociceptive somato-sensitivity are well observed in neuropathic pain. The importance of epigenetic mechanisms in regulating the...

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Detalles Bibliográficos
Autores principales: Zhu, Xiao-Yan, Huang, Chang-Sheng, Li, Qian, Chang, Rui-min, Song, Zong-bing, Zou, Wang-yuan, Guo, Qu-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558366/
https://www.ncbi.nlm.nih.gov/pubmed/23176208
http://dx.doi.org/10.1186/1744-8069-8-84

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