JC virus detection and JC virus-specific immunity in natalizumab-treated Multiple Sclerosis patients

BACKGROUND: The use of natalizumab in multiple sclerosis (MS) may favour JC virus reactivation; this phenomenon is usually asymptomatic but can, albeit rarely, evolve into frank progressive multifocal leucoencephalopathy (PML). METHODS: JCV-specific CD8+ T lymphocytes were evaluated by flow cytometr...

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Detalles Bibliográficos
Autores principales: Mancuso, Roberta, Saresella, Marina, Hernis, Ambra, Marventano, Ivana, Ricci, Cristian, Agostini, Simone, Rovaris, Marco, Caputo, Domenico, Clerici, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558446/
https://www.ncbi.nlm.nih.gov/pubmed/23232085
http://dx.doi.org/10.1186/1479-5876-10-248

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