Membrane-displayed somatostatin activates somatostatin receptor subtype-2 heterologously produced in Saccharomyces cerevisiae

The G-protein-coupled receptor (GPCR) superfamily, which includes somatostatin receptors (SSTRs), is one of the most important drug targets in the pharmaceutical industry. The yeast Saccharomyces cerevisiae is an attractive host for the ligand screening of human GPCRs. Here, we demonstrate the utili...

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Detalles Bibliográficos
Autores principales: Hara, Keisuke, Shigemori, Tomohiro, Kuroda, Kouichi, Ueda, Mitsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558460/
https://www.ncbi.nlm.nih.gov/pubmed/23193953
http://dx.doi.org/10.1186/2191-0855-2-63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558460/
https://www.ncbi.nlm.nih.gov/pubmed/23193953
http://dx.doi.org/10.1186/2191-0855-2-63

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