Human Granulocytic Anaplasmosis, Japan

We retrospectively confirmed 2 cases of human Anaplasma phagocytophilum infection. Patient blood samples contained unique p44/msp2 for the pathogen, and antibodies bound to A. phagocytophilum antigens propagated in THP-1 rather than HL60 cells. Unless both cell lines are used for serodiagnosis of ri...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohashi, Norio, Gaowa, Wuritu, Kawamori, Fumihiko, Wu, Dongxing, Yoshikawa, Yuko, Chiya, Seizou, Fukunaga, Kazutoshi, Funato, Toyohiko, Shiojiri, Masaaki, Nakajima, Hideki, Hamauzu, Yoshiji, Takano, Ai, Kawabata, Hiroki, Ando, Shuji, Kishimoto, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559047/
https://www.ncbi.nlm.nih.gov/pubmed/23460988
http://dx.doi.org/10.3201/eid1902.120855
Descripción
Sumario:We retrospectively confirmed 2 cases of human Anaplasma phagocytophilum infection. Patient blood samples contained unique p44/msp2 for the pathogen, and antibodies bound to A. phagocytophilum antigens propagated in THP-1 rather than HL60 cells. Unless both cell lines are used for serodiagnosis of rickettsiosis-like infections, cases of human granulocytic anaplasmosis could go undetected.

Ejemplares similares