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Internalization of Locked Nucleic Acids/DNA Hybrid Oligomers into Escherichia coli

Delivery inside the cells is essential for practical application of antisense technologies. The hybrid locked nucleic acid (LNA)/DNA CAAGTACTGTTCCACCA (LNA residues are underlined) was labeled by conjugation to Alexa Fluor 488 (fLNA/DNA) and tested to determine its ability to penetrate Escherichia c...

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Detalles Bibliográficos
Autores principales:	Traglia, German M., Sala, Carol Davies, Fuxman Bass, Juan I., Soler-Bistué, Alfonso J.C., Zorreguieta, Angeles, Ramírez, María Soledad, Tolmasky, Marcelo E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2012
Materias:	Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559211/ https://www.ncbi.nlm.nih.gov/pubmed/23515318 http://dx.doi.org/10.1089/biores.2012.0257

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