Integrating High-Content Imaging and Chemical Genetics to Probe Host Cellular Pathways Critical for Yersinia Pestis Infection

The molecular machinery that regulates the entry and survival of Yersinia pestis in host macrophages is poorly understood. Here, we report the development of automated high-content imaging assays to quantitate the internalization of virulent Y. pestis CO92 by macrophages and the subsequent activatio...

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Detalles Bibliográficos
Autores principales: Kota, Krishna P., Eaton, Brett, Lane, Douglas, Ulrich, Melanie, Ulrich, Ricky, Peyser, Brian D., Robinson, Camenzind G., Jaissle, James G., Pegoraro, Gianluca, Bavari, Sina, Panchal, Rekha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559335/
https://www.ncbi.nlm.nih.gov/pubmed/23383093
http://dx.doi.org/10.1371/journal.pone.0055167

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