Cargando…

TGF-β/Smad2/3 Signaling Directly Regulates Several miRNAs in Mouse ES Cells and Early Embryos

The Transforming Growth Factor-β (TGF-β) signaling pathway is one of the major pathways essential for normal embryonic development and tissue homeostasis, with anti-tumor but also pro-metastatic properties in cancer. This pathway directly regulates several target genes that mediate its downstream fu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Redshaw, Nicholas, Camps, Carme, Sharma, Vikas, Motallebipour, Mehdi, Guzman-Ayala, Marcela, Oikonomopoulos, Spyros, Thymiakou, Efstathia, Ragoussis, Jiannis, Episkopou, Vasso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559380/ https://www.ncbi.nlm.nih.gov/pubmed/23390484 http://dx.doi.org/10.1371/journal.pone.0055186

Ejemplares similares

Rnf165/Ark2C Enhances BMP-Smad Signaling to Mediate Motor Axon Extension
por: Kelly, Claire E., et al.
Publicado: (2013)

Graded Smad2/3 Activation Is Converted Directly into Levels of Target Gene Expression in Embryonic Stem Cells
por: Guzman-Ayala, Marcela, et al.
Publicado: (2009)

Correction: Graded Smad2/3 Activation Is Converted Directly into Levels of Target Gene Expression in Embryonic Stem Cells
por: Guzman-Ayala, Marcela, et al.
Publicado: (2009)

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2
por: Choudhry, Hani, et al.
Publicado: (2014)

Improved Nanopore full-length cDNA sequencing by PCR-suppression
por: Bayega, Anthony, et al.
Publicado: (2022)

Nanopore long-read RNA-seq and absolute quantification delineate transcription dynamics in early embryo development of an insect pest
por: Bayega, Anthony, et al.
Publicado: (2021)

Benchmarking of the Oxford Nanopore MinION sequencing for quantitative and qualitative assessment of cDNA populations
por: Oikonomopoulos, Spyros, et al.
Publicado: (2016)

Methodologies for Transcript Profiling Using Long-Read Technologies
por: Oikonomopoulos, Spyros, et al.
Publicado: (2020)

Arkadia Enhances Nodal/TGF-β Signaling by Coupling Phospho-Smad2/3 Activity and Turnover
por: Mavrakis, Konstantinos J, et al.
Publicado: (2007)

TGF-β Repressors SnoN and Ski Are Implicated in Human Colorectal Carcinogenesis
por: Bravou, Vasiliki, et al.
Publicado: (2009)

Association of microRNA-221/222 and -323-3p with rheumatoid arthritis via predictions using the human TNF transgenic mouse model
por: Pandis, Ioannis, et al.
Publicado: (2012)

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits
por: Wong, Daniel, et al.
Publicado: (2011)

Arkadia-SKI/SnoN signaling differentially regulates TGF-β–induced iTreg and Th17 cell differentiation
por: Xu, Hao, et al.
Publicado: (2021)

Directed Neural Differentiation of Mouse Embryonic Stem Cells Is a Sensitive System for the Identification of Novel Hox Gene Effectors
por: Bami, Myrto, et al.
Publicado: (2011)

Evolution of naturally arising SARS-CoV-2 defective interfering particles
por: Girgis, Samer, et al.
Publicado: (2022)

IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages
por: Saliba, David G., et al.
Publicado: (2014)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

TGF-Beta Induced Erk Phosphorylation of Smad Linker Region Regulates Smad Signaling
por: Hough, Chris, et al.
Publicado: (2012)

SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4
por: Bertrand-Chapel, Adrien, et al.
Publicado: (2022)

Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer
por: Choudhry, Hani, et al.
Publicado: (2014)

Smad4-mediated TGF-β signaling in tumorigenesis
por: Yang, Guan, et al.
Publicado: (2010)

The regulation of TGF-β/SMAD signaling by protein deubiquitination
por: Zhang, Juan, et al.
Publicado: (2014)

The role of TGF-β/SMAD4 signaling in cancer
por: Zhao, Ming, et al.
Publicado: (2018)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Effect of progesterone on Smad signaling and TGF-β/Smad-regulated genes in lung epithelial cells
por: Kunzmann, Steffen, et al.
Publicado: (2018)

Molecular analysis of FOXC1 in subjects presenting with severe developmental eye anomalies
por: Kaur, Kulvinder, et al.
Publicado: (2009)

The expression of TGF-β1, Smad3, phospho-Smad3 and Smad7 is correlated with the development and invasion of nonfunctioning pituitary adenomas
por: Zhenye, Li, et al.
Publicado: (2014)

Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway
por: Kang, Heeseog, et al.
Publicado: (2020)

TGF-β and TGF-β/Smad Signaling in the Interactions between Echinococcus multilocularis and Its Hosts
por: Wang, Junhua, et al.
Publicado: (2013)

Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
por: Lan, Hui Yao
Publicado: (2011)

Roles of TGFβ signaling Smads in squamous cell carcinoma
por: Han, Gangwen, et al.
Publicado: (2011)

Non-degradative ubiquitination in Smad-dependent TGF-β signaling
por: Tang, Liu-Ya, et al.
Publicado: (2011)

Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination
por: Xie, Feng, et al.
Publicado: (2014)

Rejuvenation by inhibiting TGF-β1/pSmad signaling
por: Corder, Elizabeth H., et al.
Publicado: (2015)

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
por: Walton, Kelly L., et al.
Publicado: (2017)

TGF-β/Smad Signalling in Neurogenesis: Implications for Neuropsychiatric Diseases
por: Hiew, Lih-Fhung, et al.
Publicado: (2021)

Immunohistochemical Expression of TGF-Β1, SMAD4, SMAD7, TGFβRII and CD68-Positive TAM Densities in Papillary Thyroid Cancer
por: Ivanova, Koni, et al.
Publicado: (2018)

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes
por: Herrera, Blanca M, et al.
Publicado: (2009)

Spatio-Temporal Distribution of Smads and Role of Smads/TGF-β/BMP-4 in the Regulation of Mouse Bladder Organogenesis
por: Islam, Syed S., et al.
Publicado: (2013)

TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion
por: Zhang, Chao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rmdu75e5ah43r6616hn4oc51sl