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Novel Mechanism of Inhibition of Dendritic Cells Maturation by Mesenchymal Stem Cells via Interleukin-10 and the JAK1/STAT3 Signaling Pathway

Mesenchymal stem cells (MSCs) can suppress dendritic cells (DCs) maturation and function, mediated by soluble factors, such as indoleamine 2,3-dioxygenase (IDO), prostaglandin E(2) (PGE(2)), and nitric oxide (NO). Interleukin-10 (IL-10) is a common immunosuppressive cytokine, and the downstream sign...

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Detalles Bibliográficos
Autores principales:	Liu, Wen-hua, Liu, Jing-jin, Wu, Jian, Zhang, Lu-lu, Liu, Fang, Yin, Li, Zhang, Mao-mao, Yu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559548/ https://www.ncbi.nlm.nih.gov/pubmed/23383203 http://dx.doi.org/10.1371/journal.pone.0055487

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