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An Agent-Based Model of Cellular Dynamics and Circadian Variability in Human Endotoxemia
As cellular variability and circadian rhythmicity play critical roles in immune and inflammatory responses, we present in this study an agent-based model of human endotoxemia to examine the interplay between circadian controls, cellular variability and stochastic dynamics of inflammatory cytokines....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559552/ https://www.ncbi.nlm.nih.gov/pubmed/23383223 http://dx.doi.org/10.1371/journal.pone.0055550 |