Cargando…
Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia
Human bocavirus (HBoV) was recently discovered in children with respiratory distress and/or diarrhea. To our knowledge, no previous study has reported the existence of bocavirus in Saudi Arabia. Swabs samples from 80 children with respiratory tract infections were examined for the presence of HBoV....
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559585/ https://www.ncbi.nlm.nih.gov/pubmed/23383205 http://dx.doi.org/10.1371/journal.pone.0055500 |
_version_ | 1782257612209782784 |
---|---|
author | Abdel-Moneim, Ahmed S. Kamel, Mahmoud M. Al-Ghamdi, Abdullhamid S. Al-Malky, Mater I. R. |
author_facet | Abdel-Moneim, Ahmed S. Kamel, Mahmoud M. Al-Ghamdi, Abdullhamid S. Al-Malky, Mater I. R. |
author_sort | Abdel-Moneim, Ahmed S. |
collection | PubMed |
description | Human bocavirus (HBoV) was recently discovered in children with respiratory distress and/or diarrhea. To our knowledge, no previous study has reported the existence of bocavirus in Saudi Arabia. Swabs samples from 80 children with respiratory tract infections were examined for the presence of HBoV. Real-time polymerase chain reaction was used as a sensitive method to detect the HBoV. Direct gene sequencing was used to determine the genotype of the detected virus isolates. HBoV was detected in 22.5% of the examined patients. The NP1 partial gene sequence from all patients showed that the circulated strains were related to HBoV-1 genotype. Most of HBoV infected patients showed evidence of mixed coinfection with other viral pathogens. The current study clearly demonstrated that genetically conserved HBoV1 circulates in Saudi Arabia. Interestingly, most of the HBoV1 infected cases were associated with high rates of co-infections with other viruses. |
format | Online Article Text |
id | pubmed-3559585 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-35595852013-02-04 Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia Abdel-Moneim, Ahmed S. Kamel, Mahmoud M. Al-Ghamdi, Abdullhamid S. Al-Malky, Mater I. R. PLoS One Research Article Human bocavirus (HBoV) was recently discovered in children with respiratory distress and/or diarrhea. To our knowledge, no previous study has reported the existence of bocavirus in Saudi Arabia. Swabs samples from 80 children with respiratory tract infections were examined for the presence of HBoV. Real-time polymerase chain reaction was used as a sensitive method to detect the HBoV. Direct gene sequencing was used to determine the genotype of the detected virus isolates. HBoV was detected in 22.5% of the examined patients. The NP1 partial gene sequence from all patients showed that the circulated strains were related to HBoV-1 genotype. Most of HBoV infected patients showed evidence of mixed coinfection with other viral pathogens. The current study clearly demonstrated that genetically conserved HBoV1 circulates in Saudi Arabia. Interestingly, most of the HBoV1 infected cases were associated with high rates of co-infections with other viruses. Public Library of Science 2013-01-30 /pmc/articles/PMC3559585/ /pubmed/23383205 http://dx.doi.org/10.1371/journal.pone.0055500 Text en © 2013 Abdel-Moneim et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Abdel-Moneim, Ahmed S. Kamel, Mahmoud M. Al-Ghamdi, Abdullhamid S. Al-Malky, Mater I. R. Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia |
title | Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia |
title_full | Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia |
title_fullStr | Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia |
title_full_unstemmed | Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia |
title_short | Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia |
title_sort | detection of bocavirus in children suffering from acute respiratory tract infections in saudi arabia |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559585/ https://www.ncbi.nlm.nih.gov/pubmed/23383205 http://dx.doi.org/10.1371/journal.pone.0055500 |
work_keys_str_mv | AT abdelmoneimahmeds detectionofbocavirusinchildrensufferingfromacuterespiratorytractinfectionsinsaudiarabia AT kamelmahmoudm detectionofbocavirusinchildrensufferingfromacuterespiratorytractinfectionsinsaudiarabia AT alghamdiabdullhamids detectionofbocavirusinchildrensufferingfromacuterespiratorytractinfectionsinsaudiarabia AT almalkymaterir detectionofbocavirusinchildrensufferingfromacuterespiratorytractinfectionsinsaudiarabia |