Cargando…

AAV9 Targets Cone Photoreceptors in the Nonhuman Primate Retina

Transduction of retinal pigment epithelial cells with an adeno-associated viral vector (AAV) based on serotype 2 has partially corrected retinal blindness in Leber congenital amaurosis type 2. However, many applications of gene therapy for retinal blindness rely on the efficient transduction of rod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vandenberghe, Luk H., Bell, Peter, Maguire, Albert M., Xiao, Ru, Hopkins, Tim B., Grant, Rebecca, Bennett, Jean, Wilson, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559681/ https://www.ncbi.nlm.nih.gov/pubmed/23382846 http://dx.doi.org/10.1371/journal.pone.0053463

Ejemplares similares

Correction: AAV9 Targets Cone Photoreceptors in the Nonhuman Primate Retina
por: Vandenberghe, Luk H., et al.
Publicado: (2013)

AAV-mediated photoreceptor transduction of the pig cone-enriched retina
por: Mussolino, C, et al.
Publicado: (2011)

Axonal transport of AAV9 in nonhuman primate brain
por: Green, Foad, et al.
Publicado: (2016)

S-cone photoreceptors in the primate retina are functionally distinct from L and M cones
por: Baudin, Jacob, et al.
Publicado: (2019)

Generation of Nonhuman Primate Model of Cone Dysfunction through In Situ AAV-Mediated CNGB3 Ablation
por: Lin, Qiang, et al.
Publicado: (2020)

No evidence for loss of short-wavelength sensitive cone photoreceptors in normal ageing of the primate retina
por: Weinrich, Tobias W., et al.
Publicado: (2017)

Recent Advancements in AAV-Vectored Immunoprophylaxis in the Nonhuman Primate Model
por: Campbell, Elena S. B., et al.
Publicado: (2023)

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates
por: Ohno, Kousaku, et al.
Publicado: (2018)

Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection
por: Wassmer, Sarah J., et al.
Publicado: (2017)

Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution
por: Aboualizadeh, Ebrahim, et al.
Publicado: (2020)

Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington’s disease
por: Hadaczek, Piotr, et al.
Publicado: (2016)

An S-cone circuit for edge detection in the primate retina
por: Patterson, Sara S., et al.
Publicado: (2019)

Origin and Impact of Phototransduction Noise in Primate Cone Photoreceptors
por: Angueyra, Juan Manuel, et al.
Publicado: (2013)

Canine Retina Has a Primate Fovea-Like Bouquet of Cone Photoreceptors Which Is Affected by Inherited Macular Degenerations
por: Beltran, William A., et al.
Publicado: (2014)

Host Immune Responses after Suprachoroidal Delivery of AAV8 in Nonhuman Primate Eyes
por: Chung, Sook Hyun, et al.
Publicado: (2021)

Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system
por: Campos, Lillian J., et al.
Publicado: (2023)

Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates
por: Zhang, Longlong, et al.
Publicado: (2023)

Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates
por: Mattar, Citra N., et al.
Publicado: (2015)

Intra-CSF AAV9 and AAVrh10 Administration in Nonhuman Primates: Promising Routes and Vectors for Which Neurological Diseases?
por: Bey, Karim, et al.
Publicado: (2020)

Topographical characterization of cone photoreceptors and the area centralis of the canine retina
por: Mowat, Freya M., et al.
Publicado: (2008)

Conditional and biased regeneration of cone photoreceptor types in the zebrafish retina
por: D'Orazi, Florence D., et al.
Publicado: (2020)

A Novel Device for Suprachoroidal Drug Delivery to Retina: Evaluation in Nonhuman Primates
por: Rotenstreich, Ygal, et al.
Publicado: (2023)

Nonhuman Primate Models for SARS
por: Haagmans, Bart L, et al.
Publicado: (2006)

Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates
por: Yiu, Glenn, et al.
Publicado: (2020)

Ablation of Ctrp9, Ligand of AdipoR1, and Lower Number of Cone Photoreceptors in Mouse Retina
por: Inooka, Daiki, et al.
Publicado: (2022)

LINC Complexes Mediate the Positioning of Cone Photoreceptor Nuclei in Mouse Retina
por: Razafsky, David, et al.
Publicado: (2012)

A method for isolation of cone photoreceptors from adult zebrafish retinae
por: Glaviano, Antonino, et al.
Publicado: (2016)

Noninvasive Imaging and Correlative Histology of Cone Photoreceptor Structure in the Pig Retina
por: Huckenpahler, Alison L., et al.
Publicado: (2019)

Association of Shank 1A Scaffolding Protein with Cone Photoreceptor Terminals in the Mammalian Retina
por: Stella, Salvatore L., et al.
Publicado: (2012)

Assessment of Tropism and Effectiveness of New Primate-Derived Hybrid Recombinant AAV Serotypes in the Mouse and Primate Retina
por: Charbel Issa, Peter, et al.
Publicado: (2013)

Aging in nonhuman primates /
Publicado: (1979)

Behavior of Nonhuman Primates
por: Southwick, Charles H.
Publicado: (1966)

Pharmacological Modulation of Humoral Immunity in a Nonhuman Primate Model of AAV Gene Transfer for Hemophilia B
por: Mingozzi, Federico, et al.
Publicado: (2012)

Safety and tolerability of MRI-guided infusion of AAV2-hAADC into the mid-brain of nonhuman primate
por: Sebastian, Waldy San, et al.
Publicado: (2014)

Timing of Intensive Immunosuppression Impacts Risk of Transgene Antibodies after AAV Gene Therapy in Nonhuman Primates
por: Samelson-Jones, Benjamin J., et al.
Publicado: (2020)

Avian Cone Photoreceptors Tile the Retina as Five Independent, Self-Organizing Mosaics
por: Kram, Yoseph A., et al.
Publicado: (2010)

Imaging Ca(2+) Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
por: Kulkarni, Manoj, et al.
Publicado: (2015)

Peptide-guided lipid nanoparticles deliver mRNA to the neural retina of rodents and nonhuman primates
por: Herrera-Barrera, Marco, et al.
Publicado: (2023)

Modeling Cone/Cone–Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina
por: Wang, Yuwei, et al.
Publicado: (2021)

Efficient expression of self-complementary AAV in ganglion cells of the ex vivo primate retina
por: Koilkonda, Rajeshwari D., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_p6ouc76bue5g96v7op70guoe57