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Metabolites of Ginger Component [6]-Shogaol Remain Bioactive in Cancer Cells and Have Low Toxicity in Normal Cells: Chemical Synthesis and Biological Evaluation
Our previous study found that [6]-shogaol, a major bioactive component in ginger, is extensively metabolized in cancer cells and in mice. It is unclear whether these metabolites retain bioactivity. The aim of the current study is to synthesize the major metabolites of [6]-shogaol and evaluate their...
Autores principales: | Zhu, Yingdong, Warin, Renaud F., Soroka, Dominique N., Chen, Huadong, Sang, Shengmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559867/ https://www.ncbi.nlm.nih.gov/pubmed/23382939 http://dx.doi.org/10.1371/journal.pone.0054677 |
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