Expression of AFP and STAT3 Is Involved in Arsenic Trioxide-Induced Apoptosis and Inhibition of Proliferation in AFP-Producing Gastric Cancer Cells

Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and...

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Detalles Bibliográficos
Autores principales: Jia, Yanfei, Liu, Dezhi, Xiao, Dongjie, Ma, Xiaoli, Han, Shuyi, Zheng, Yan, Sun, Shanhui, Zhang, Maoxiu, Gao, Hongmei, Cui, Xia, Wang, Yunshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559880/
https://www.ncbi.nlm.nih.gov/pubmed/23382965
http://dx.doi.org/10.1371/journal.pone.0054774

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