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Neurotrophic and Neuroprotective Actions of (−)- and (+)-Phenserine, Candidate Drugs for Alzheimer’s Disease

Neuronal dysfunction and demise together with a reduction in neurogenesis are cardinal features of Alzheimer’s disease (AD) induced by a combination of oxidative stress, toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration of these was assessed with the Aβ lowering AD expe...

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Detalles Bibliográficos
Autores principales: Lilja, Anna M., Luo, Yu, Yu, Qian-sheng, Röjdner, Jennie, Li, Yazhou, Marini, Ann M., Marutle, Amelia, Nordberg, Agneta, Greig, Nigel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559887/
https://www.ncbi.nlm.nih.gov/pubmed/23382994
http://dx.doi.org/10.1371/journal.pone.0054887