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Neurotrophic and Neuroprotective Actions of (−)- and (+)-Phenserine, Candidate Drugs for Alzheimer’s Disease
Neuronal dysfunction and demise together with a reduction in neurogenesis are cardinal features of Alzheimer’s disease (AD) induced by a combination of oxidative stress, toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration of these was assessed with the Aβ lowering AD expe...
Autores principales: | Lilja, Anna M., Luo, Yu, Yu, Qian-sheng, Röjdner, Jennie, Li, Yazhou, Marini, Ann M., Marutle, Amelia, Nordberg, Agneta, Greig, Nigel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559887/ https://www.ncbi.nlm.nih.gov/pubmed/23382994 http://dx.doi.org/10.1371/journal.pone.0054887 |
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