Cargando…

Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties

An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimid...

Descripción completa

Detalles Bibliográficos
Autores principales: Gradauer, K., Dünnhaupt, S., Vonach, C., Szöllösi, H., Pali-Schöll, I., Mangge, H., Jensen-Jarolim, E., Bernkop-Schnürch, A., Prassl, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560037/
https://www.ncbi.nlm.nih.gov/pubmed/23228848
http://dx.doi.org/10.1016/j.jconrel.2012.12.001