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A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses
BACKGROUND: Despite progress in the development of combined antiretroviral therapies (cART), HIV infection remains a significant challenge for human health. Current problems of cART include multi-drug-resistant virus variants, long-term toxicity and enormous treatment costs. Therefore, the identific...
Autores principales: | Prokofjeva, Maria M, Riecken, Kristoffer, Spirin, Pavel V, Yanvarév, Dimitriy V, Düsedau, Arne, Ellinger, Bernhard, Fehse, Boris, Stocking, Carol, Prassolov, Vladimir S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560153/ https://www.ncbi.nlm.nih.gov/pubmed/23286882 http://dx.doi.org/10.1186/1742-6405-10-1 |
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