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An integrative analysis of cellular contexts, miRNAs and mRNAs reveals network clusters associated with antiestrogen-resistant breast cancer cells

BACKGROUND: A major goal of the field of systems biology is to translate genome-wide profiling data (e.g., mRNAs, miRNAs) into interpretable functional networks. However, employing a systems biology approach to better understand the complexities underlying drug resistance phenotypes in cancer contin...

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Detalles Bibliográficos
Autores principales: Nam, Seungyoon, Long, Xinghua, Kwon, ChangHyuk, Kim, Sun, Nephew, Kenneth P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560207/
https://www.ncbi.nlm.nih.gov/pubmed/23270413
http://dx.doi.org/10.1186/1471-2164-13-732