Indoleamine-2,3-dioxygenase activity in experimental human endotoxemia

BACKGROUND: Excessive tryptophan metabolism to kynurenine by the rate-limiting enzyme endothelial indoleamine 2,3-dioxygenase 1 (IDO) controls arterial vessel relaxation and causes hypotension in murine endotoxemia. However, its relevance in human endotoxemia has not been investigated so far. We thu...

Descripción completa

Detalles Bibliográficos
Autores principales: Padberg, Jan-Sören, Van Meurs, Matijs, Kielstein, Jan T, Martens-Lobenhoffer, Jens, Bode-Böger, Stefanie M, Zijlstra, Jan G, Kovesdy, Csaba P, Kümpers, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560239/
https://www.ncbi.nlm.nih.gov/pubmed/23216784
http://dx.doi.org/10.1186/2040-7378-4-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560239/
https://www.ncbi.nlm.nih.gov/pubmed/23216784
http://dx.doi.org/10.1186/2040-7378-4-24

Ejemplares similares