Detection of Histone Modifications at Specific Gene Loci in Single Cells in Histological Sections

Chromatin immunoprecipitation (ChIP) assays have contributed greatly to our understanding of the role of histone modifications in gene regulation. However, a major limitation is that they do not permit analysis with single cell resolution thus confounding analyses of heterogeneous cell populations....

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Detalles Bibliográficos
Autores principales: Gomez, Delphine, Shankman, Laura L, Nguyen, Anh T, Owens, Gary K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560316/
https://www.ncbi.nlm.nih.gov/pubmed/23314172
http://dx.doi.org/10.1038/nmeth.2332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560316/
https://www.ncbi.nlm.nih.gov/pubmed/23314172
http://dx.doi.org/10.1038/nmeth.2332

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