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Detection of Histone Modifications at Specific Gene Loci in Single Cells in Histological Sections
Chromatin immunoprecipitation (ChIP) assays have contributed greatly to our understanding of the role of histone modifications in gene regulation. However, a major limitation is that they do not permit analysis with single cell resolution thus confounding analyses of heterogeneous cell populations....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560316/ https://www.ncbi.nlm.nih.gov/pubmed/23314172 http://dx.doi.org/10.1038/nmeth.2332 |