Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report

BACKGROUND: Organophosphorus compounds (OP) are a group of substances used in agriculture as pesticides and are also used as military poisoning agents (MPA). Intoxication by these agents may cause severe systemic disturbances related to both the exposure time and lethal agent concentration. Toxic ef...

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Autores principales: Ryniak, Stan, Harbut, Piotr, GoŸdzik, Waldemar, Sokołowski, Janusz, Paciorek, Przemysław, Hałas, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2011
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560512/
https://www.ncbi.nlm.nih.gov/pubmed/21873952
http://dx.doi.org/10.12659/MSM.881922
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author Ryniak, Stan
Harbut, Piotr
GoŸdzik, Waldemar
Sokołowski, Janusz
Paciorek, Przemysław
Hałas, Joanna
author_facet Ryniak, Stan
Harbut, Piotr
GoŸdzik, Waldemar
Sokołowski, Janusz
Paciorek, Przemysław
Hałas, Joanna
author_sort Ryniak, Stan
collection PubMed
description BACKGROUND: Organophosphorus compounds (OP) are a group of substances used in agriculture as pesticides and are also used as military poisoning agents (MPA). Intoxication by these agents may cause severe systemic disturbances related to both the exposure time and lethal agent concentration. Toxic effects result from an excess of the endogenous neurotransmitter, acetylcholine (ACh), because decomposition of Ach by cholinesterases is blocked by OP. CASE REPORT: The authors describe a case in which an acute OP poisoning was managed both conventionally and with cholinesterase substitution by blood transfusion. CONCLUSIONS: Whole blood transfusion could be beneficial in the treatment of these life-threatening medical conditions.
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spelling pubmed-35605122013-04-24 Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report Ryniak, Stan Harbut, Piotr GoŸdzik, Waldemar Sokołowski, Janusz Paciorek, Przemysław Hałas, Joanna Med Sci Monit Case Study BACKGROUND: Organophosphorus compounds (OP) are a group of substances used in agriculture as pesticides and are also used as military poisoning agents (MPA). Intoxication by these agents may cause severe systemic disturbances related to both the exposure time and lethal agent concentration. Toxic effects result from an excess of the endogenous neurotransmitter, acetylcholine (ACh), because decomposition of Ach by cholinesterases is blocked by OP. CASE REPORT: The authors describe a case in which an acute OP poisoning was managed both conventionally and with cholinesterase substitution by blood transfusion. CONCLUSIONS: Whole blood transfusion could be beneficial in the treatment of these life-threatening medical conditions. International Scientific Literature, Inc. 2011-09-01 /pmc/articles/PMC3560512/ /pubmed/21873952 http://dx.doi.org/10.12659/MSM.881922 Text en © Med Sci Monit, 2011 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
spellingShingle Case Study
Ryniak, Stan
Harbut, Piotr
GoŸdzik, Waldemar
Sokołowski, Janusz
Paciorek, Przemysław
Hałas, Joanna
Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report
title Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report
title_full Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report
title_fullStr Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report
title_full_unstemmed Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report
title_short Whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report
title_sort whole blood transfusion in the treatment of an acute organophosphorus poisoning – a case report
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560512/
https://www.ncbi.nlm.nih.gov/pubmed/21873952
http://dx.doi.org/10.12659/MSM.881922
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