Coexpression of Smad7 and UPA attenuates carbon tetrachloride-induced rat liver fibrosis

BACKGROUND: There is a great need for developing novel therapies to treat liver fibrosis. Previous studies showed that both Smad7 and uPA were inhibitors of liver fibrosis. Therefore, we explored the therapeutic effects of combinational gene therapy with Smad7 and uPA on CCl4-induced liver fibrosis....

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Detalles Bibliográficos
Autores principales: Wang, Baocan, Li, Wenxi, Chen, Yingwei, Wang, Yuqin, Sun, Chao, Chen, Yuanwen, Lu, Hanming, Fan, Jiangao, Li, Dingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560566/
https://www.ncbi.nlm.nih.gov/pubmed/23018346
http://dx.doi.org/10.12659/MSM.883479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560566/
https://www.ncbi.nlm.nih.gov/pubmed/23018346
http://dx.doi.org/10.12659/MSM.883479

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