Biochemically and histopathologically comparative review of thiamine’s and thiamine pyrophosphate’s oxidative stress effects generated with methotrexate in rat liver

BACKGROUND: Oxidative liver injury occurring with methotrexate restricts its use in the desired dose. Therefore, whether or not thiamine and thiamine pyrophosphate, whose antioxidant activity is known, have protective effects on oxidative liver injury generated with methotrexate was comparatively re...

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Detalles Bibliográficos
Autores principales: Demiryilmaz, Ismail, Sener, Ebru, Cetin, Nihal, Altuner, Durdu, Suleyman, Bahadir, Albayrak, Fatih, Akcay, Fatih, Suleyman, Halis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560789/
https://www.ncbi.nlm.nih.gov/pubmed/23197226
http://dx.doi.org/10.12659/MSM.883591

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