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Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction
BACKGROUND: The aim of this study was to investigate the effects of sub-clinical alterations on the amplitudes and slopes of the DPOAE input-output responses from subjects with previous history of middle ear dysfunction. MATERIAL/METHODS: The study included 15 subjects with and 15 subjects without a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560824/ https://www.ncbi.nlm.nih.gov/pubmed/22460101 http://dx.doi.org/10.12659/MSM.882605 |
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author | Campos, Ualace De P. Sanches, Seisse G. Hatzopoulos, Stavros Carvallo, Renata M. M. Kochanek, Krzysztof Skarżyński, Henryk |
author_facet | Campos, Ualace De P. Sanches, Seisse G. Hatzopoulos, Stavros Carvallo, Renata M. M. Kochanek, Krzysztof Skarżyński, Henryk |
author_sort | Campos, Ualace De P. |
collection | PubMed |
description | BACKGROUND: The aim of this study was to investigate the effects of sub-clinical alterations on the amplitudes and slopes of the DPOAE input-output responses from subjects with previous history of middle ear dysfunction. MATERIAL/METHODS: The study included 15 subjects with and 15 subjects without a history of otitis media in the last 10 years. All participants were assessed with acoustic immittance, pure-tone audiometry, and DPOAEs. For the later, I/O functions and I/O slopes were estimated at 1501, 2002, 3174, 4004 and 6384Hz. RESULTS: No statistically significant differences were found between the 2 groups in terms of behavioral thresholds. The group with a previous history of middle ear dysfunction presented significantly lower mean DPOAE amplitudes at 2002, 3174 and 4004 Hz. In terms of DPOAE slopes, no statistically significant differences were observed at the tested frequencies, except at 3174 Hz. CONCLUSIONS: Middle ear pathologies can produce subclinical alterations that are undetectable with traditional pure-tone audiometry. The data from the present study show that reduced amplitude DPOAEs are associated with a previous history of middle ear complications. The corresponding DPOAE slopes were affected at only 1 tested frequency, suggesting that the cochlear non-linearity is preserved. Considering these results, it remains to be elucidated to what degree the DPOAE amplitude attenuation interferes with higher-order auditory tasks. |
format | Online Article Text |
id | pubmed-3560824 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-35608242013-04-24 Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction Campos, Ualace De P. Sanches, Seisse G. Hatzopoulos, Stavros Carvallo, Renata M. M. Kochanek, Krzysztof Skarżyński, Henryk Med Sci Monit Diagnostics and Medical Technology BACKGROUND: The aim of this study was to investigate the effects of sub-clinical alterations on the amplitudes and slopes of the DPOAE input-output responses from subjects with previous history of middle ear dysfunction. MATERIAL/METHODS: The study included 15 subjects with and 15 subjects without a history of otitis media in the last 10 years. All participants were assessed with acoustic immittance, pure-tone audiometry, and DPOAEs. For the later, I/O functions and I/O slopes were estimated at 1501, 2002, 3174, 4004 and 6384Hz. RESULTS: No statistically significant differences were found between the 2 groups in terms of behavioral thresholds. The group with a previous history of middle ear dysfunction presented significantly lower mean DPOAE amplitudes at 2002, 3174 and 4004 Hz. In terms of DPOAE slopes, no statistically significant differences were observed at the tested frequencies, except at 3174 Hz. CONCLUSIONS: Middle ear pathologies can produce subclinical alterations that are undetectable with traditional pure-tone audiometry. The data from the present study show that reduced amplitude DPOAEs are associated with a previous history of middle ear complications. The corresponding DPOAE slopes were affected at only 1 tested frequency, suggesting that the cochlear non-linearity is preserved. Considering these results, it remains to be elucidated to what degree the DPOAE amplitude attenuation interferes with higher-order auditory tasks. International Scientific Literature, Inc. 2012-04-01 /pmc/articles/PMC3560824/ /pubmed/22460101 http://dx.doi.org/10.12659/MSM.882605 Text en © Med Sci Monit, 2012 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. |
spellingShingle | Diagnostics and Medical Technology Campos, Ualace De P. Sanches, Seisse G. Hatzopoulos, Stavros Carvallo, Renata M. M. Kochanek, Krzysztof Skarżyński, Henryk Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction |
title | Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction |
title_full | Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction |
title_fullStr | Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction |
title_full_unstemmed | Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction |
title_short | Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction |
title_sort | alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction |
topic | Diagnostics and Medical Technology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560824/ https://www.ncbi.nlm.nih.gov/pubmed/22460101 http://dx.doi.org/10.12659/MSM.882605 |
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