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Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identif...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560991/ https://www.ncbi.nlm.nih.gov/pubmed/23369517 http://dx.doi.org/10.1186/2001-1326-1-9 |
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author | Fang, Xiaocong Bai, Chunxue Wang, Xiangdong |
author_facet | Fang, Xiaocong Bai, Chunxue Wang, Xiangdong |
author_sort | Fang, Xiaocong |
collection | PubMed |
description | Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identify new therapeutic targets. Acute lung injurt (ALI)/Acute respiratory distress syndrome (ARDS) affects a large number of patients with a poor prognosis. The present review mainly focused on the progress in understanding disease heterogeneity through the use of evolving biological, genomic, and genetic approaches and the role of clinical bioinformatics in the pathogenesis and treatment of ALI/ARDS. The remarkable advances in clinical bioinformatics can be a new way for understanding disease pathogenesis, diagnosis and treatment. |
format | Online Article Text |
id | pubmed-3560991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Springer |
record_format | MEDLINE/PubMed |
spelling | pubmed-35609912013-02-04 Bioinformatics insights into acute lung injury/acute respiratory distress syndrome Fang, Xiaocong Bai, Chunxue Wang, Xiangdong Clin Transl Med Review Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identify new therapeutic targets. Acute lung injurt (ALI)/Acute respiratory distress syndrome (ARDS) affects a large number of patients with a poor prognosis. The present review mainly focused on the progress in understanding disease heterogeneity through the use of evolving biological, genomic, and genetic approaches and the role of clinical bioinformatics in the pathogenesis and treatment of ALI/ARDS. The remarkable advances in clinical bioinformatics can be a new way for understanding disease pathogenesis, diagnosis and treatment. Springer 2012-06-09 /pmc/articles/PMC3560991/ /pubmed/23369517 http://dx.doi.org/10.1186/2001-1326-1-9 Text en Copyright ©2012 Fang et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License(http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Fang, Xiaocong Bai, Chunxue Wang, Xiangdong Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title | Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_full | Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_fullStr | Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_full_unstemmed | Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_short | Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_sort | bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560991/ https://www.ncbi.nlm.nih.gov/pubmed/23369517 http://dx.doi.org/10.1186/2001-1326-1-9 |
work_keys_str_mv | AT fangxiaocong bioinformaticsinsightsintoacutelunginjuryacuterespiratorydistresssyndrome AT baichunxue bioinformaticsinsightsintoacutelunginjuryacuterespiratorydistresssyndrome AT wangxiangdong bioinformaticsinsightsintoacutelunginjuryacuterespiratorydistresssyndrome |