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Bioinformatics insights into acute lung injury/acute respiratory distress syndrome

Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identif...

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Detalles Bibliográficos
Autores principales: Fang, Xiaocong, Bai, Chunxue, Wang, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560991/
https://www.ncbi.nlm.nih.gov/pubmed/23369517
http://dx.doi.org/10.1186/2001-1326-1-9
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author Fang, Xiaocong
Bai, Chunxue
Wang, Xiangdong
author_facet Fang, Xiaocong
Bai, Chunxue
Wang, Xiangdong
author_sort Fang, Xiaocong
collection PubMed
description Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identify new therapeutic targets. Acute lung injurt (ALI)/Acute respiratory distress syndrome (ARDS) affects a large number of patients with a poor prognosis. The present review mainly focused on the progress in understanding disease heterogeneity through the use of evolving biological, genomic, and genetic approaches and the role of clinical bioinformatics in the pathogenesis and treatment of ALI/ARDS. The remarkable advances in clinical bioinformatics can be a new way for understanding disease pathogenesis, diagnosis and treatment.
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spelling pubmed-35609912013-02-04 Bioinformatics insights into acute lung injury/acute respiratory distress syndrome Fang, Xiaocong Bai, Chunxue Wang, Xiangdong Clin Transl Med Review Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identify new therapeutic targets. Acute lung injurt (ALI)/Acute respiratory distress syndrome (ARDS) affects a large number of patients with a poor prognosis. The present review mainly focused on the progress in understanding disease heterogeneity through the use of evolving biological, genomic, and genetic approaches and the role of clinical bioinformatics in the pathogenesis and treatment of ALI/ARDS. The remarkable advances in clinical bioinformatics can be a new way for understanding disease pathogenesis, diagnosis and treatment. Springer 2012-06-09 /pmc/articles/PMC3560991/ /pubmed/23369517 http://dx.doi.org/10.1186/2001-1326-1-9 Text en Copyright ©2012 Fang et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License(http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Fang, Xiaocong
Bai, Chunxue
Wang, Xiangdong
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
title Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
title_full Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
title_fullStr Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
title_full_unstemmed Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
title_short Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
title_sort bioinformatics insights into acute lung injury/acute respiratory distress syndrome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560991/
https://www.ncbi.nlm.nih.gov/pubmed/23369517
http://dx.doi.org/10.1186/2001-1326-1-9
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