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Rapamycin and mTOR: a serendipitous discovery and implications for breast cancer
Rapamycin was discovered more than thirty years ago from a soil sample from the island of Rapa Nui. It was isolated from Streptomyces hygroscopicus and initial characterization focused on its antifungal activities. Subsequent characterization showed that it has immunosuppressive properties and has b...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561035/ https://www.ncbi.nlm.nih.gov/pubmed/23369283 http://dx.doi.org/10.1186/2001-1326-1-29 |