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Dot1-Dependent Histone H3K79 Methylation Promotes Activation of the Mek1 Meiotic Checkpoint Effector Kinase by Regulating the Hop1 Adaptor
During meiosis, accurate chromosome segregation relies on the proper interaction between homologous chromosomes, including synapsis and recombination. The meiotic recombination checkpoint is a quality control mechanism that monitors those crucial events. In response to defects in synapsis and/or rec...
Autores principales: | Ontoso, David, Acosta, Isabel, van Leeuwen, Fred, Freire, Raimundo, San-Segundo, Pedro A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561090/ https://www.ncbi.nlm.nih.gov/pubmed/23382701 http://dx.doi.org/10.1371/journal.pgen.1003262 |
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