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Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated rat

BACKGROUND: The acute response to genotoxic carcinogens in rats is an important model for researching cancer initiation events. In this report we define the normal rat colonic epithelium by describing transcriptional events along the anterior-posterior axis and then investigate the acute effects of...

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Detalles Bibliográficos
Autores principales:	Kerr, Caroline A, Hines, Barney M, Shaw, Janet M, Dunne, Robert, Bragg, Lauren M, Clarke, Julie, Lockett, Trevor, Head, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561103/ https://www.ncbi.nlm.nih.gov/pubmed/23343511 http://dx.doi.org/10.1186/1472-6793-13-2

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