Cargando…

Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated rat

BACKGROUND: The acute response to genotoxic carcinogens in rats is an important model for researching cancer initiation events. In this report we define the normal rat colonic epithelium by describing transcriptional events along the anterior-posterior axis and then investigate the acute effects of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kerr, Caroline A, Hines, Barney M, Shaw, Janet M, Dunne, Robert, Bragg, Lauren M, Clarke, Julie, Lockett, Trevor, Head, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561103/ https://www.ncbi.nlm.nih.gov/pubmed/23343511 http://dx.doi.org/10.1186/1472-6793-13-2

Ejemplares similares

Early Alterations of Apoptosis and Cell Proliferation in Azoxymethane‐initiated Rat Colonic Epithelium
por: Hirose, Yoshinobu, et al.
Publicado: (1996)

Measuring the combinatorial expression of solute transporters and metalloproteinases transcripts in colorectal cancer
por: Kerr, Caroline A, et al.
Publicado: (2009)

Enhancement by neurotensin of experimental carcinogenesis induced in rat colon by azoxymethane.
por: Tasuta, M., et al.
Publicado: (1990)

Inhibition by isoproterenol and neostigmine of experimental carcinogenesis in rat colon by azoxymethane.
por: Tatsuta, M., et al.
Publicado: (1988)

Combinational Effects of Prebiotics and Soybean against Azoxymethane-Induced Colon Cancer In Vivo
por: Gourineni, V. P., et al.
Publicado: (2011)

Diet-Induced Obesity Promotes Colon Tumor Development in Azoxymethane-Treated Mice
por: Tuominen, Iina, et al.
Publicado: (2013)

Enhanced Development of Azoxymethane-Induced Colonic Preneoplastic Lesions in Hypertensive Rats
por: Kochi, Takahiro, et al.
Publicado: (2013)

Chemopreventive Efficacy of Andrographis paniculata on Azoxymethane-Induced Aberrant Colon Crypt Foci In Vivo
por: Al-Henhena, Nawal, et al.
Publicado: (2014)

Deletion of Glutathione Peroxidase-2 Inhibits Azoxymethane-Induced Colon Cancer Development
por: Müller, Mike F., et al.
Publicado: (2013)

Inhibition of Azoxymethane‐induced Colon Carcinogenesis in Rat by Green Tea Polyphenol Fraction
por: Yamane, Testsuro, et al.
Publicado: (1991)

Induction of Apoptosis by Sulindac in Azoxymethane‐induced Possible Colonic Premalignant Lesions in Rats
por: Kuno, Toshiya, et al.
Publicado: (2002)

Increased Cell Proliferation of Azoxymethane‐induced Aberrant Crypt Foci of Rat Colon
por: Yamashita, Naoyuki, et al.
Publicado: (1994)

Increase in dietary protein content exacerbates colonic inflammation and tumorigenesis in azoxymethane-induced mouse colon carcinogenesis
por: Tak, Ka-Hee, et al.
Publicado: (2017)

Resistant Starches Protect against Colonic DNA Damage and Alter Microbiota and Gene Expression in Rats Fed a Western Diet(2)
por: Conlon, Michael A., et al.
Publicado: (2012)

Morphological and Molecular Alterations in 1,2 Dimethylhydrazine and Azoxymethane Induced Colon Carcinogenesis in Rats
por: Perše, Martina, et al.
Publicado: (2011)

Amelioration of azoxymethane induced-carcinogenesis by reducing oxidative stress in rat colon by natural extracts
por: Waly, Mostafa I, et al.
Publicado: (2014)

American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in mice
por: Yu, Chunhao, et al.
Publicado: (2014)

The Effect of Sex on the Azoxymethane/Dextran Sulfate Sodium-treated Mice Model of Colon Cancer
por: Lee, Sun Min, et al.
Publicado: (2016)

Suppression of Azoxymethane‐induced Rat Colon Aberrant Crypt Foci by Dietary Protocatechuic Acid
por: Kawamori, Toshihiko, et al.
Publicado: (1994)

Effects of Apple Pectin on Fecal Bacterial Enzymes in Azoxymethane‐induced Rat Colon Carcinogenesis
por: Ohkami, Hideo, et al.
Publicado: (1995)

Inhibition of Azoxymethane‐initiated Colon Tumor by Bovine Lactoferrin Administration in F344 Rats
por: Sekine, Kazunori, et al.
Publicado: (1997)

Açaí Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice
por: Choi, Yoon Jin, et al.
Publicado: (2017)

Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer
por: Refaat, Bassem, et al.
Publicado: (2016)

Chemopreventive effects of Strobilanthes crispus leaf extract on azoxymethane-induced aberrant crypt foci in rat colon
por: Al-Henhena, Nawal, et al.
Publicado: (2015)

Contribution of ATOH1(+) Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium
por: Ishibashi, Fumiaki, et al.
Publicado: (2017)

Global gene expression analysis of the mouse colonic mucosa treated with azoxymethane and dextran sodium sulfate
por: Suzuki, Rikako, et al.
Publicado: (2007)

Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon
por: Simmen, Frank A, et al.
Publicado: (2009)

Role of Hepatic and Intestinal P450 Enzymes in the Metabolic Activation of the Colon Carcinogen Azoxymethane in Mice
por: Megaraj, Vandana, et al.
Publicado: (2014)

Inhibitory Effect of Spirulina maxima on the Azoxymethane-induced Aberrant Colon Crypts and Oxidative Damage in Mice
por: Álvarez-González, Isela, et al.
Publicado: (2015)

Correction: Chemopreventive Efficacy of Andrographis paniculata on Azoxymethane-Induced Aberrant Colon Crypt Foci In Vivo
Publicado: (2015)

Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer
por: Ruderman, Sarah, et al.
Publicado: (2018)

Dietary Conjugated Linolenic Acid Inhibits Azoxymethane‐induced Colonic Aberrant Crypt Foci in Rats
por: Kohno, Hiroyuki, et al.
Publicado: (2002)

Regressive Effects of Various Chemopreventive Agents on Azoxymethane‐induced Aberrant Crypt Foci in the Rat Colon
por: Morishita, Yukio, et al.
Publicado: (1997)

Dysregulated Notch Signaling in the Airway Epithelium of Children with Wheeze
por: Iosifidis, Thomas, et al.
Publicado: (2021)

SARS-CoV-2 Infection Dysregulates Cilia and Basal Cell Homeostasis in the Respiratory Epithelium of Hamsters
por: Schreiner, Tom, et al.
Publicado: (2022)

Luteolin, a bioflavonoid inhibits azoxymethane-induced colon carcinogenesis: Involvement of iNOS and COX-2
por: Pandurangan, Ashok Kumar, et al.
Publicado: (2014)

Supplementation of Seaweeds Extracts Suppresses Azoxymethane-induced Aberrant DNA Methylation in Colon and Liver of ICR Mice
por: Bu, So Young, et al.
Publicado: (2014)

Evaluation of Chemopreventive Effects of Acanthus ilicifolius against Azoxymethane-Induced Aberrant Crypt Foci in the Rat Colon
por: Almagrami, Amel A., et al.
Publicado: (2014)

Chemoprevention of Azoxymethane‐induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1′‐Acetoxychavicol Acetate
por: Tanaka, Takuji, et al.
Publicado: (1997)

Alpha-Glucosidase Inhibitor Voglibose Suppresses Azoxymethane-Induced Colonic Preneoplastic Lesions in Diabetic and Obese Mice
por: Kato, Junichi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d1tvvcrhinb06nmbvjvdev0meo